Fuzzy clustering method can analyze complex data sets more effectively.Because there are many kinds of fuzzy clustering algorithms and Allen Wrench the clustering results will change with the number of input clusters,the results of fuzzy clustering algorithm are not accurate,so the number of fuzzy clustering k must be determined in order to obtain
The dirhodium(II)-catalyzed organic reactions, including asymmetric transformation, are significantly benefitted from the discovery of simple and efficient protocols to introduce various bridging ligands, e.g.carboxylic Remote Control acids, amide and phosphoric acids.Ligands lying at axial position of dirhodium(II) complexes could strongly affect
Hong Jiang,1,* Zhi-Peng Li,1,* Gui-Xiang Tian,1,* Rui-Yan Pan,1 Chong-Mei Xu,2 Bo Zhang,2 Jing-liang Wu1 1School of Bioscience and Technology, Weifang Medical University, Antennas Weifang, Shandong, China; 2School of Pharmacy, Weifang Medical University, Weifang, Shandong, China *These authors contributed equally to this work Background: Recent eff
Niemann-Pick C (NPC) disease is an autosomal recessive disorder that leads to excessive storage of cholesterol and other lipids in late endosomes and lysosomes.The large majority of NPC disease is caused by mutations in NPC1, a large polytopic membrane protein that functions in late Choke endosomes.There are many disease-associated mutations in NPC